Three large studies find screening reduces mortality for those with detectable type 2 diabetes but not for general population: /s00125-017-4323- 2 ...
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A significant innovation was the shift key , introduced with the Remington No. 2 in 1878. This key physically "shifted" either the basket of typebars, in which case the typewriter is described as "basket shift", or the paper-holding carriage, in which case the typewriter is described as "carriage shift". Either mechanism caused a different portion of the typebar to come in contact with the ribbon/platen. The result is that each typebar could type two different characters, cutting the number of keys and typebars in half (and simplifying the internal mechanisms considerably). The obvious use for this was to allow letter keys to type both upper and lower case, but normally the number keys were also duplexed, allowing access to special symbols such as percent (%) and ampersand (&).